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R&D Systems™ Recombinant Mouse 4-1BB/TNFRSF9 Fc Chimera Protein

Product Code. 18166830
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Quantity:
50 μg
Unit Size:
50µg
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Product Code. Quantity unitSize
18166830 50 μg 50µg
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Product Code. 18166830 Supplier R&D Systems™ Supplier No. 9374B050

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Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility. Applications: Bioactivity, Binding Activity

Measured by its ability to block 4-1BBL-induced IL-2 secretion by mouse T cells. The ED50 for this effect is 0.3-1 μg/mL in the presence of 0.4 μg/mL of recombinant mouse 4-1BBL. Measured by its ability to bind recombinant mouse 4-1BB Ligand in a functional ELISA.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P20334
For Use With (Application) Bioactivity, Binding Activity
Formulation Lyophilized from a 0.2 μm filtered solution in PBS.
Gene ID (Entrez) 3604
Molecular Weight (g/mol) M.W. (Observed): 62-66 kDa, reducing conditions; M.W. (theoretical): 44.3 kDa (monomer)
Quantity 50 μg
Source Mouse myeloma cell line, NS0-derived mouse 4-1 BB/TNFRSF9/CD137 protein Mouse 4-1 BB (Val24-Leu187) (N-terminus) Accession # P20334 DIEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
Storage Requirements Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
Structural Form Disulfide-linked homodimer
Endotoxin Concentration <0.10 EU / 1 μg of the protein by the LAL method.
Gene Symbol Tnfrsf9
Product Type 4-1BB/TNFRSF9/CD137 Fc Chimera
Conjugate Unconjugated
Species Mouse
Recombinant Recombinant
Reconstitution Reconstitute at 100 μg/mL in sterile PBS.
Purity or Quality Grade >95%, by SDS-PAGE under reducing conditions and visualized by silver stain
Protein 4-1 BB/TNFRSF9/CD137
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