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R&D Systems™ Recombinant Human PD-L1/B7-H1 Fc Chimera Protein

Product Code. 18166880
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Quantity:
100 μg
Unit Size:
100µg
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Product Code. Quantity unitSize
18166880 100 μg 100µg
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Product Code. 18166880 Supplier R&D Systems™ Supplier No. 156B7100

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Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility. Applications: Bioactivity

Measured by its ability to inhibit anti-CD3 antibody induced IL-2 secretion in human T lymphocytes. The ED50 for this effect is 0.075-0.75 μg/mL.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q9NZQ7
For Use With (Application) Bioactivity
Formulation Lyophilized from a 0.2 μm filtered solution in PBS and NaCl.
Gene ID (Entrez) 29126
Molecular Weight (g/mol) M.W. (Observed): 70-75 kDa, reducing conditions; M.W. (theoretical): 52 kDa (monomer)
Name B7-H1/PD-L1 Fc Chimera
Quantity 100 μg
Source Mouse myeloma cell line, NS0-derived human PD-L1/B7-H1 protein Human PD-L1 (Phe19-Thr239) (N-terminus) Accession # Q9NZQ7 DIEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
Storage Requirements Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
Structural Form Disulfide-linked homodimer
Endotoxin Concentration <0.01 EU / 1 μg of the protein by the LAL method.
Gene Symbol CD274
Conjugate Unconjugated
Recombinant Recombinant
Reconstitution Reconstitute at 100 μg/mL in sterile PBS.
Purity or Quality Grade >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
Protein PD-L1
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