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DiscoverX Ready-to-Assay™ SST3 Somatostatin Receptor Frozen Cells

Product Code. 17395309
Encompass
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Quantity:
2 Vials of Cells
Unit Size:
2 ampoules
This item is not returnable. View return policy

Product Code. 17395309

Brand: DiscoverX HTS171RTA

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This item is not returnable. View return policy

Description

The Ready-to-Assay™ SST3 Somatostatin Receptor Frozen Cells measure SSTR3 (GPCR) activation via an increase in intracellular calcium. Ready-to-Assay kits contain two vials of thaw-and-use cells.

The Ready-to-Assay™ SST3 Somatostatin Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. somatostatin) based activation of SSTR3 GPCR activity via detection of increasing levels of intracellular calcium. The included cells overexpress SSTR3 alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of SSTR3, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the cells in a convenient thaw-and-use format.

Specifications

Assay Entry SST3
For Use With (Application) Frozen Cells
Primary Agonist somatostatin
Quantity 2 Vials of Cells
Target Entry SSTR3
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