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Invitrogen™ RASA4 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA531934
This item is not returnable.
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Description
Recommended positive controls: HepG2. Predicted reactivity: Mouse (84%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene.
Specifications
| RASA4 | |
| Polyclonal | |
| Unconjugated | |
| RASA4 | |
| AA793972; AW112107; BB079060; Ca2+promoted Ras inactivator; Ca2+-promoted Ras inactivator; calcium-promoted RAS inactivator; Capri; GAPL; Kiaa0538; Ras GTPase-activating protein 4; RAS p21 protein activator 4; RASA4; RasGAP-activating-like protein 2; RGD1565457 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 10156 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot | |
| 0.71 mg/mL | |
| 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7 | |
| O43374 | |
| RASA4 | |
| Recombinant protein encompassing a sequence within the N-terminus region of human RASA4. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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