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Rapamycin, MedChemExpress

Artikelnummer. 16451546
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16451546 500 mg 500mg
16450979 1 g 1g
16440956 200 mg 200mg
16430076 2 g 2g
16420107 50 mg 50mg
16404796 100 mg 100mg
16436457 5 g 5g
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Artikelnummer. 16451546 Leverandør Medchem Express Leverandørnr. HY10219

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Beskrivelse

MedChemExpress Rapamycin (Sirolimus; AY 22989) is a potent and specific mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant.

Rapamycin (Sirolimus

Tekniske data

Chemical Name or Material Rapamycin
CAS 53123-88-9
Color White
Purity Grade Notes Research
Molecular Formula C51H79NO13
Quantity 500 mg
Synonym Sirolimus AY-22989
Solubility Information DMSO : 125 mg/mL (136.74 mM; Need ultrasonic) ∣Ethanol : 50 mg/mL (54.69 mM; Need ultrasonic)
SMILES O=C([C@@]1(O)[C@@H](CC[C@@H](C[C@@H](/C(C)=C/C=C/C=C/[C@H](C[C@@H](C)C([C@@H]([C@@H](/C(C)=C/[C@H]2C)O)OC)=O)C)OC)O1)C)C(N3CCCC[C@H]3C(O[C@@H](CC2=O)[C@@H](C[C@H]4C[C@H]([C@H](O)CC4)OC)C)=O)=O
Molecular Weight (g/mol) 914.17
Formula Weight 914.17
Percent Purity 98.0%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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