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Invitrogen™ RACGAP1 Monoclonal Antibody (23A8)

Description
Recommended positive controls: rat brain microsomal protein. MA1-20580 detects a band of approximately 21 kDa.
RAC, a small GTPase in the ras family, regulates the formation of membrane ruffles, lamellipodia and filopodia. It is involved in cytoskeletal actin organization and transformation. The p21 activated kinases (PAKs) are direct targets of active Rac and Cdc42 which can induce the assembly of polarized cytoskeletal structures when expressed in fibroblasts. RAC1 and RAC2 are also essential components of NADPH oxidase, the enzyme responsible for generating free radicals.
Specifications
Specifications
| Antigen | RACGAP1 |
| Applications | Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot |
| Classification | Monoclonal |
| Clone | 23A8 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | TBS with 30% glycerol and 0.05% sodium azide |
| Gene | RACGAP1 |
| Gene Accession No. | Q9H0H5, Q9WVM1 |
| Gene Alias | AI227039; AI327394; AKT; Band25; CYK4; GAP; gtl11; GTPase; HsCYK-4; ID; ID-GAP; KIAA1478; Male germ cell RacGap; MGC99656; MgcRacGAP; mKIAA1478; PKB; PKB-ALPHA; PRKBA; protein CYK4 homolg; Protein CYK4 homolog; RAC; Rac GTPase activating protein 1; Rac GTPase-activating protein 1; RAC-ALPHA; Racgap1 |
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