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PYZD-4409, MedChemExpress

Product Code. 16466156
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Product Code. 16466156 Supplier Medchem Express Supplier No. HY13297

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Description

MedChemExpress PYZD-4409 is a specific inhibitor of the ubiquitin-activating enzyme UBA1 with an IC50 of 20 μM (cell-free enzymatic assay). PYZD-4409 induces cell death in malignant cells and preferentially inhibits the clonogenic growth of primary acute myeloid leukemia cells.

PYZD-4409 is a specific inhibitor of the ubiquitin-activating enzyme UBA1 with an IC50 of 20 μM (cell-free enzymatic assay). PYZD-4409 induces cell death in malignant cells and preferentially inhibits the clonogenic growth of primary acute myeloid leukemia cells.

Specifications

Chemical Name or Material PYZD-4409
CAS 423148-78-1
Color Light Brown to Black
Purity Grade Notes Research
Molecular Formula C14H7ClFN3O5
Quantity 100 mg
Solubility Information DMSO : ≥ 35 mg/mL (99.53 mM)
SMILES FC1=CC=C(N2C(/C(C(N2)=O)=C\C3=CC=C([N+]([O-])=O)O3)=O)C=C1Cl
Molecular Weight (g/mol) 351.67
Formula Weight 351.67
Percent Purity 98.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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