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PSMB7 Monoclonal Antibody (OTI4G9), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Brand: Origene Technologies TA504383
This item is not returnable.
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Description
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon and proteolytic processing is required to generate a mature subunit. This subunit is not present in the immunoproteasome and is replaced by catalytic subunit 2i (proteasome beta 10 subunit).Specifications
| PSMB7 | |
| Monoclonal | |
| 0.59 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| P70195, Q99436, Q9JHW0 | |
| PSMB7 | |
| Human recombit protein fragment corresponding to amino acids 58-277 of human PSMB7 produced in E.coli. | |
| 100 μL | |
| Primary | |
| Canine, Human, Mouse, Rat | |
| Antibody | |
| IgG1 |
| Immunocytochemistry, Immunofluorescence, Western Blot | |
| OTI4G9 | |
| Unconjugated | |
| PSMB7 | |
| Z | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 100686423, 19177, 5695, 85492 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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