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Tocris Bioscience™ PROTAC™(H-PGDS)-7

Product Code. 30000409
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5 mg
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Product Code. 30000409 Supplier Tocris Bioscience™ Supplier No. 8004/5

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329.00 EUR valid until 2026-03-31
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Description

Potent hematopoietic prostaglandin D2 synthase Degrader (PROTAC™)

PROTAC™(H-PGDS)-7 is a potent Degrader of hematopoietic prostaglandin D2 synthase (H-PGDS; DC50 = 17pM after 24 hours). Comprises the H-PGDS inhibitor TFC-007 (Cat. No. 5108) directly linked to E3 ligase cereblon. Suppresses prostaglandin D2 production in vitro and in vivo. PROTAC™(H-PGDS)-8 negative control (Cat. No. 8005) also available.PROTAC™ is a registered trademark of Arvinas Operations, Inc., and is used under license.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material N-[4-[4-[[4-[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-1-piperazinyl]carbonyl]-1-piperidinyl]phenyl]-2-phenoxy-5-pyrimidinecarboxamide
CAS 2761281-50-7
Quantity 5 mg
Target Active Degraders
Molecular Formula C40H38N8O7
Purity 98%
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