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Invitrogen™ Profilin 1 Polyclonal Antibody
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Product Code. 13491737
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Quantity:
100 μL
Unit Size:
100µL
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13491737 100 μL 100µL
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Product Code. 13491737 Supplier Invitrogen™ Supplier No. PA527612

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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, HeLa, HepG2, mouse spleen, Rat spleen. Predicted reactivity: Mouse (95%), Rat (95%), Pig (94%), Bovine (93%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Profilin is an ubiquitous small (12-15 kDa) phosphoinositides and poly-L-proline binding protein that plays a role in both signal transduction pathways and actin filament dynamics. There are two mammalian profilins with similar biochemical properties but different expression patterns. Profilin I appears to be highly expressed in most tissues except for skeletal muscle. Profilin II is predominantly expressed in brain and at lower levels in skeletal muscle, uterus and kidney. Profilin is a mainly cytosolic protein with higher concentrations in dynamic membrane areas like the leading edge and ruffling membranes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Profilin 1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.56 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Pfn1
Gene Accession No. P07737, P62962, P62963
Gene Alias actin binding protein; ALS18; Epididymis tissue protein Li 184a; Pfn; Pfn1; profilin 1; profilin I; Profilin-1
Gene Symbols Pfn1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human Profilin 1. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18643, 5216, 64303
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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