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Invitrogen™ PRL1 Polyclonal Antibody
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Product Code. 17827372
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Quantity:
100 μg
Unit Size:
100µL
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Product Code. Quantity unitSize
17827372 100 μg 100µL
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Product Code. 17827372 Supplier Invitrogen™ Supplier No. PA5142119

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Description

Goat Polyclonal Antibody

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:64,000.

The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This tyrosine phosphatase is a nuclear protein, but may primarily associate with plasma membrane. The surface membrane association of this protein depends on its C-terminal prenylation. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which implicated its role in the tumorigenesis. Studies in rat suggested that this gene may be an immediate-early gene in mitogen-stimulated cells. PRL phosphatases increase cell proliferation by stimulating progression from G1 into S phase. PRL-1 function is regulated in a cell cycle-dependent manner and implicate PRL-1 in regulating progression through mitosis, possibly by modulating spindle dynamics.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PRL1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene PTP4A1
Gene Accession No. Q63739, Q93096
Gene Alias AA415290; AU019864; C130021B01; DKFZp779M0721; HH72; PRL1; Prl-1; protein tyrosine phosphatase 4a1; protein tyrosine phosphatase type IVA 1; protein tyrosine phosphatase type IVA protein 1; protein tyrosine phosphatase type IVA, member 1; protein-tyrosine phosphatase 4a1; Protein-tyrosine phosphatase of regenerating liver 1; PTP(CAAX1); PTP(CAAXI); PTP4A1; PTP4A1 protein; PTP4A2; PTPCAAX1; RP5-1148A21.2
Gene Symbols PTP4A1
Host Species Goat
Immunogen Peptide with sequence CFKDSNGHRNN.
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19243, 7803
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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