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  6. PRE-084 hydrochloride, MedChemExpress

PRE-084 hydrochloride, MedChemExpress

Product Code. p-200102010
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Product Code. 16473487 Supplier Medchem Express Supplier No. HY18100A

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Description

MedChemExpress PRE-084 hydrochloride is a highly selective σ1 receptor (S1R) agonist, with an IC50 of 44 nM. PRE-084 hydrochloride exhibits good neuroprotective effects, can improve motor function and motor neuron survival in mice. PRE-084 hydrochloride also can ameliorate myocardial ischemia-reperfusion injury in rats by activating the Akt-eNOS pathway.

PRE-084 hydrochloride is a highly selective σ1 receptor (S1R) agonist, with an IC50 of 44 nM. PRE-084 hydrochloride exhibits good neuroprotective effects, can improve motor function and motor neuron survival in mice. PRE-084 hydrochloride also can ameliorate myocardial ischemia-reperfusion injury in rats by activating the Akt-eNOS pathway.

Specifications

Chemical Name or Material PRE-084 hydrochloride
Physical Form Solid
CAS 75136-54-8
Color White
Quantity 50 mg
Purity Grade Notes Research
Molecular Formula C19H28ClNO3
For Use With (Application) Neuroscience-Neuromodulation
Solubility Information DMSO : ≥ 34 mg/mL (96.08 mM) ∣H2O : 33.33 mg/mL (94.18 mM; ultrasonic and warming and heat to 60°C)
SMILES O=C(C1(C2=CC=CC=C2)CCCCC1)OCCN3CCOCC3.[H]Cl
Molecular Weight (g/mol) 353.88
Formula Weight 353.88
Percent Purity 99.38%
Grade Research
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