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POLR3H Mouse anti-Human, Clone: OTI4D8, lyophilized, TrueMAB™

Product Code. 17630512
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Quantity:
100 μg
Unit Size:
100µg
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17630512 100 μg 100µg
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Product Code. 17630512 Supplier Origene Technologies Supplier No. CF809432

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Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

RPC8 is DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. It is plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. It is acting as nuclear and cytosolic DNA sensor involved in innate immune response. It can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF-Kappa-B through the RIG-I pathway.

Specifications

Antigen POLR3H
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI4D8
Conjugate Unconjugated
Formulation PBS with 8% trehalose and no preservative; pH 7.3
Gene POLR3H
Gene Accession No. Q9Y535
Gene Alias RPC22.9, RPC8
Gene Symbols POLR3H
Host Species Mouse
Immunogen Full length human recombit protein of human POLR3H produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 171568
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG1
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