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POLG2 Polyclonal Antibody, Invitrogen™
Description
This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal domit progressive external ophthalmoplegia with mitochondrial DNA deletions.
Specifications
Specifications
| Antigen | POLG2 |
| Applications | Immunohistochemistry (Paraffin) |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gene | POLG2 |
| Gene Accession No. | Q9UHN1, Q9QZM2 |
| Gene Alias | DNA polymerase subunit gamma-2, mitochondrial, Mitochondrial DNA polymerase accessory subunit, PolG-beta, MtPolB, DNA polymerase gamma accessory 55 kDa subunit, p55, POLG2, MTPOLB |
| Gene Symbols | POLG2 |
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