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PLX-4720, MedChemExpress

Product Code. 16424067
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 16424067

Brand: Medchem Express HY51424

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Description

MedChemExpress PLX-4720 is a potent and selective inhibitor of B-RafV600E with IC50 of 13 nM in a cell-free assay, equally potent to c-Raf-1(Y340D and Y341D mutations), and 10-fold selectivity for B-RafV600E than wild-type B-Raf.

PLX-4720 is a potent and selective inhibitor of B-RafV600E with IC50 of 13 nM in a cell-free assay, equally potent to c-Raf-1(Y340D and Y341D mutations), and 10-fold selectivity for B-RafV600E than wild-type B-Raf.

Specifications

Chemical Name or Material PLX-4720
CAS 918505-84-7
Color White
Purity Grade Notes Research
Molecular Formula C17H14ClF2N3O3S
Quantity 50 mg
Solubility Information DMSO : 100 mg/mL (241.65 mM; Need ultrasonic)
SMILES O=S(NC1=CC=C(C(C(C2=CNC3=NC=C(C=C23)Cl)=O)=C1F)F)(CCC)=O
Molecular Weight (g/mol) 413.83
Formula Weight 413.83
Percent Purity 98.35%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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