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Pico145, MedChemExpress

Product Code. 16459926
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Product Code. 16459926 Supplier Medchem Express Supplier No. HY101507

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Description

MedChemExpress Pico145 (HC-608) is a remarkable inhibitor of TRPC1/4/5 channels, inhibits (−)-englerin A-activated TRPC4/TRPC5 channels, with IC50s of 0.349 and 1.3 nM in cells, and shows no effect on TRPC3, TRPC6, TRPV1, TRPV4, TRPA1, TRPM2, TRPM8.

Pico145 (HC-608) is a remarkable inhibitor of TRPC1/4/5 channels, inhibits (−)-englerin A-activated TRPC4/TRPC5 channels, with IC50s of 0.349 and 1.3 nM in cells, and shows no effect on TRPC3, TRPC6, TRPV1, TRPV4, TRPA1, TRPM2, TRPM8.

Specifications

Chemical Name or Material Pico145
CAS 1628287-16-0
Color Pink
Purity Grade Notes Research
Molecular Formula C23H20ClF3N4O5
Quantity 50 mg
Synonym HC-608
Solubility Information DMSO : ≥ 100 mg/mL (190.52 mM)
SMILES O=C1C2=C(N=C(OC3=CC=CC(OC(F)(F)F)=C3)N2CC4=CC=C(Cl)C=C4)N(C)C(N1CCCO)=O
Molecular Weight (g/mol) 524.88
Formula Weight 524.88
Percent Purity 98.62%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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