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PI-103, MedChemExpress

Product Code. 16414546
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Product Code. 16414546

Brand: Medchem Express HY10115

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Description

MedChemExpress PI-103 is a potent PI3K and mTOR inhibitor with IC50s of 8 nM, 88 nM, 48 nM, 150 nM, 20 nM, and 83 nM for p110α, p110β, p110δ, p110γ, mTORC1, and mTORC2. PI-103 also inhibits DNA-PK with an IC50 of 2 nM. PI-103 induces autophagy.

PI-103 is a potent PI3K and mTOR inhibitor with IC50s of 8 nM, 88 nM, 48 nM, 150 nM, 20 nM, and 83 nM for p110α, p110β, p110δ, p110γ, mTORC1, and mTORC2. PI-103 also inhibits DNA-PK with an IC50 of 2 nM. PI-103 induces autophagy.

Specifications

Chemical Name or Material PI-103
CAS 371935-74-9
Color Light Green
Purity Grade Notes Research
Molecular Formula C19H16N4O3
Quantity 100 mg
Solubility Information DMSO : 10 mg/mL (28.71 mM; Need ultrasonic)
SMILES OC1=CC(C2=NC3=C(C(N4CCOCC4)=N2)OC5=C3C=CC=N5)=CC=C1
Molecular Weight (g/mol) 348.36
Formula Weight 348.36
Percent Purity 98.01%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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