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Invitrogen™ Phospho-HDAC5 (Ser498) Polyclonal Antibody
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Product Code. 16681485
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Quantity:
100 μL
Unit Size:
100µL
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16681485 100 μL 100µL
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Product Code. 16681485 Supplier Invitrogen™ Supplier No. PA5105041

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of HDAC5 only when phosphorylated at Serine 498.

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-HDAC5 (Ser498)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene HDAC5
Gene Accession No. Q9UQL6, Q9Z2V6
Gene Alias AI426555; Antigen NY-CO-9; DKFZp779K1053; FLJ90614; HD5; HD7; HD7b; HD9; HDAC; Hdac4; HDAC5; HDAC-5; HDAC7; HDAC7B; HDAC9; HDAC9B; HDAC9FL; HDRP; histone deacetylase 4; histone deacetylase 5; histone deacetylase mHDA1; KIAA0600; KIAA0744; mHDA1; mKIAA0600; NY-CO-9
Gene Symbols HDAC5
Host Species Rabbit
Immunogen A synthesized peptide derived from human HDAC5(Accession Q9UQL6), corresponding to amino acid residues around phosphorylated Ser498.
Purification Method Sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10014, 15184, 84580
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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