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PFI-2 hydrochloride, MedChemExpress
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
Description
PFI-2 ((R)-PFI-2 hydrochloride) hydrochloride is a potent and selective SET domain containing lysine methyltransferase 7 (SETD7) inhibitor. (R)-PFI-2 shows high inhibiting activity with IC50 value of 2.0 nM and (S)-PFI-2 shows inhibiting activity with IC50 value of 1.0 μM. PFI-2 hydrochloride can be used for the research of chronic kidney disease and inflammation response in the development of renal fibrosis.
Specifications
Specifications
| Chemical Name or Material | PFI-2 hydrochloride |
| CAS | 1627607-87-7 |
| Color | White |
| Purity Grade Notes | Research |
| Molecular Formula | C23H26ClF4N3O3S |
| Quantity | 50 mg |
| Synonym | (R)-PFI-2 hydrochloride |
| Solubility Information | DMSO : ≥ 32 mg/mL (59.70 mM) ∣H2O : 5.56 mg/mL (10.37 mM; Need ultrasonic) |
| SMILES | O=S(C1=CC2=C(CNCC2)C(F)=C1)(N[C@H](CC3=CC=CC(C(F)(F)F)=C3)C(N4CCCC4)=O)=O.[H]Cl |
| Molecular Weight (g/mol) | 535.98 |
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Research purposes only
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