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Tocris Bioscience™ PF 3084014 hydrobromide
Potent γ-secretase inhibitor
Brand: Tocris Bioscience™ 5751/50
This item is not returnable.
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Description
PF 3084014 hydrobromide is a potent γ-secretase inhibitor (IC50 values are 1.2 and 6.2 nM in whole cell and cell-free assays, respectively). Reduces Aβ in brain, CSF and plasma in mice and guinea pigs.Specifications
| (2 S)-2-[[(2 S)-6,8-Difluoro-1,2,3,4-tetrahydro-2-naphthalenyl]amino]-N-[1-[2-[(2,2-dimethylpropyl)amino]-1,1-dimethylethyl]-1 H-imidazol-4-yl]pentanamide dihydrobromide | |
| 1962925-29-6 | |
| 50 mg |
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