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  5. Tocris Bioscience™ PF 04620110

Tocris Bioscience™ PF 04620110
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Product Code. 18781388
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Quantity:
25 mg
Unit Size:
25mg
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Product Code. 18781388

Brand: Tocris Bioscience™ 5863/25

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This item is not returnable. View return policy

Description

Potent and selective DGAT-1 inhibitor; orally bioavailable

PF 04620110 is a potent and selective DGAT-1 inhibitor (IC50 = 19 nM). Exhibits >1000-fold selectivity for DGAT-1 over DGAT-2, and no significant activity against a range of other enzymes, ion channels and receptors. Reduces plasma triglyceride levels in a rat lipid challenge model. Orally bioavailable.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material trans-4-[4-(4-Amino-7,8-dihydro-5-oxopyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)phenyl]cyclohexaneacetic acid
CAS 1109276-89-2
Assay Percent Range >98%
Quantity 25 mg
Molecular Formula C21H24N4O4
Formula Weight Observed MW: 396.44
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