missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. 30000991

Tocris Bioscience™ Pemetrexed
GREENER_CHOICE

Product Code. 30000991
Click to view available options
Quantity:
50 mg
Unit Size:
50mg
This item is not returnable. View return policy

Product Code. 30000991

Brand: Tocris Bioscience™ 6185/50

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

High affinity dihydrofolate reductase inhibitor; also inhibits thymidylate synthase, GARFT and AICART

High affinity dihydrofolate reductase inhibitor (Ki = 7 nM). Also inhibits thymidylate synthase, AICART and glycinamide ribonucleotide formyltransferase (Ki values are 109 nM, and 3.5 μM and 9.3 μM, respectively). Indirectly activates AMPK. Inhibits proliferation of cancer cell lines in vitro.
TRUSTED_SUSTAINABILITY

Specifications

CAS 137281-23-3
Quantity 50 mg
Solubility Soluble to 100mM in DMSO
Molecular Formula C20H21N5O6
Formula Weight 427.41
Physical Form Solid
Purity >98%
Molecular Weight (g/mol) 427.417
Chemical Name or Material N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.