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Pemetrexed disodium, MedChemExpress

Product Code. 16485136
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Product Code. 16485136 Supplier Medchem Express Supplier No. HY10820A

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Description

MedChemExpress Pemetrexed disodium (LY231514 disodium) is an antifolate, the Kis of the pentaglutamate of Pemetrexed disodium are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively.

Pemetrexed disodium (LY231514 disodium) is an antifolate, the Kis of the pentaglutamate of Pemetrexed disodium are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively.

Specifications

Chemical Name or Material Pemetrexed disodium
CAS 150399-23-8
Color White
Purity Grade Notes Research
Molecular Formula C20H19N5Na2O6
Quantity 100 mg
Synonym LY231514 disodium
Solubility Information H2O : ≥ 100 mg/mL (212.15 mM)
SMILES O=C1NC(N)=NC2=C1C(CCC3=CC=C(C=C3)C(N[C@@H](CCC(O[Na])=O)C(O[Na])=O)=O)=CN2
Molecular Weight (g/mol) 471.37
Formula Weight 471.37
Percent Purity 99.23%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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