missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. STEMCELL Technologies PD98059

STEMCELL Technologies PD98059

Product Code. 17170032
Encompass_Preferred
Click to view available options
Quantity:
1 mg
5 mg
Unit Size:
1mg
5mg
This item is not returnable. View return policy

Product Code. 17170032

Brand: STEMCELL Technologies 72172

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

MEK/ERK pathway inhibitor; Inhibits MEK1 and MEK2

  • PD98059 is a selective, cell permeable inhibitor of the MEK/ERK pathway that acts by preventing the activation of MEK1 (IC50 = 2 - 7 μM) and MEK2 (IC50 = 50 μM) by upstream kinases
  • It does not inhibit activated MEK, or the p38 MAPK pathway
  • (Alessi et al.), Davies et al.), Dudley et al.)
  • Enhances the growth and self-renewal of mouse embryonic stem (ES) cells (Burdon et al.), Qi et al.)
  • Permits derivation of mouse ES cells from the refractory CBA mouse strain (Buehr and Smith)
  • Blocks the differentiation of mouse ES cells (Burdon et al.)
  • Enhances adipogenic differentiation and blocks osteogenic differentiation of human mesenchymal stem cells (Jaiswal et al.)
  • Decreases number of AML blast colonies with minimal effect on normal hematopoietic progenitors (Milella et al.)

Specifications

CAS 167869-21-8
Quantity 1 mg
Molecular Formula C16H13NO3
Purity ≥98%
Product Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.