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  8. PCI 29732, MedChemExpress

PCI 29732, MedChemExpress

Product Code. 16467416
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Product Code. 16467416 Supplier Medchem Express Supplier No. HY18010

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Description

MedChemExpress PCI 29732 is a potent, orally active, reversible BTK inhibitor with Kiapp values of 8.2, 4.6, and 2.5 nM for BTK, Lck and Lyn, respectively. PCI 29732 shows only modest inhibitory activity against Itk, another Tec family kinase. PCI 29732 inhibits the function of ABCG2 by competitively binding to the ATP-binding site of ABCG2.

PCI 29732 is a potent, orally active, reversible BTK inhibitor with Kiapp values of 8.2, 4.6, and 2.5 nM for BTK, Lck and Lyn, respectively. PCI 29732 shows only modest inhibitory activity against Itk, another Tec family kinase. PCI 29732 inhibits the function of ABCG2 by competitively binding to the ATP-binding site of ABCG2.

Specifications

Chemical Name or Material PCI 29732
CAS 330786-25-9
Color Off-White
Purity Grade Notes Research
Molecular Formula C22H21N5O
Quantity 100 mg
Solubility Information DMSO : ≥ 53 mg/mL (142.69 mM) ∣Ethanol : 10 mg/mL (26.92 mM; Need ultrasonic)
SMILES NC1=NC=NC2=C1C(C3=CC=C(OC4=CC=CC=C4)C=C3)=NN2C5CCCC5
Molecular Weight (g/mol) 371.44
Formula Weight 371.44
Percent Purity 99.86%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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