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PBIT, MedChemExpress

Product Code. 16456097
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Product Code. 16456097 Supplier Medchem Express Supplier No. HY101451

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Description

MedChemExpress PBIT is a specific inhibitor of the Jumonji AT-rich Interactive Domain 1 (JARID1) enzymes. PBIT inhibits JARID1B (KDM5B or PLU1) histone demethylase with an IC50 of about 3 μM . PBIT also inhibits JARID1A and JARID1C with IC50s of 6 μM and 4.9 μM, respectively.

PBIT is a specific inhibitor of the Jumonji AT-rich Interactive Domain 1 (JARID1) enzymes. PBIT inhibits JARID1B (KDM5B or PLU1) histone demethylase with an IC50 of about 3 μM . PBIT also inhibits JARID1A and JARID1C with IC50s of 6 μM and 4.9 μM, respectively.

Specifications

Chemical Name or Material PBIT
Physical Form Solid
CAS 2514-30-9
Color Brown
Quantity 5 mg
Purity Grade Notes Research
Molecular Formula C14H11NOS
For Use With (Application) Cancer-programmed cell death
Solubility Information DMSO : 50 mg/mL (207.20 mM; Need ultrasonic)
SMILES O=C1N(C2=CC=C(C)C=C2)SC3=C1C=CC=C3
Molecular Weight (g/mol) 241.31
Formula Weight 241.31
Percent Purity 98.0%
Grade Research
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Research purposes only

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