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Invitrogen™ Parvalbumin Monoclonal Antibody (3C9)
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA547410
This item is not returnable.
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Description
Parvalbumin Monoclonal Antibody for Western Blot, IHC (PFA), ICC/IF
Parvalbumin (PV) is a calcium binding protein expressed in specific muscle fibers and fast-firing neurons. PV consists of a single, unbranched chain of linked amino acids and belongs to a larger group of EF hand proteins. Studies have demonstrated that parvalbumin acts in the decay of calcium in the contraction/ relaxation cycle of fast twitch muscles. This data has shown a positive correlation between the rate of relaxation and the concentration of parvalbumin. Parvalbumin is also expressed in a specific population of GABAergic interneurones which are thought to play a role in maintaining the balance between excitation and inhibition in the cortex as well as the hippocampus. In amyotrophic lateral sclerosis (ALS) patents, parvalbumin immunoreactivity is specifically absent from neuron populations lost early in ALS.
Specifications
| Parvalbumin | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 50% glycerol and 5mM sodium azide | |
| P02625, P20472, P32848, Q0VCG3 | |
| Pvalb | |
| Full-length recombinant human protein expressed in and purified from E. coli. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat, Bovine, Pig, Horse | |
| Antibody | |
| IgG1 |
| Immunohistochemistry (PFA fixed), Western Blot, Immunocytochemistry | |
| 3C9 | |
| Unconjugated | |
| Pvalb | |
| D22S749; HGNC:9704; MGC116759; PALB1; Parv; parvalbumin; Parvalbumin (calcium binding protein); parvalbumin alpha; PV; Pva; PVALB | |
| Mouse | |
| Protein G | |
| RUO | |
| 100069554, 100157265, 19293, 25269, 538603, 5816 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
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