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Paritaprevir, MedChemExpress
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Quantity:
5 mg
10 mg
50 mg
100 mg
Unit Size:
100mg
10mg
50mg
5mg
Description
Paritaprevir (ABT-450) is a potent, orally active and antiviral non-structural protein 3/4A (NS3/4A) protease inhibitor with EC50s of 1 and 0.21 nM against HCV 1a and 1b, respectively. Paritaprevir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.31 μM. Paritaprevir is metabolized primarily by cytochrome P450 (CYP) 3A. The plasma concentration and half-life of Paritaprevir can be enhanced by Ritonavir (a CYP450 inhibitor).
Specifications
Specifications
| Chemical Name or Material | Paritaprevir |
| CAS | 1216941-48-8 |
| Color | White |
| Purity Grade Notes | Research |
| Molecular Formula | C40H43N7O7S |
| Quantity | 100 mg |
| Synonym | ABT-450 Veruprevir |
| Solubility Information | DMSO : ≥ 125 mg/mL (163.21 mM) ∣H2O : ≥ 0.1 mg/mL (0.13 mM) |
| SMILES | O=C([C@]1(NC([C@@]2([H])N3C[C@H](OC4=C(C=CC=C5)C5=C6C(C=CC=C6)=N4)C2)=O)[C@H](/C=C\CCCCC[C@H](NC(C7=NC=C(C)N=C7)=O)C3=O)C1)NS(=O)(C8CC8)=O |
| Molecular Weight (g/mol) | 765.88 |
| Show More |
Research purposes only
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