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OAS2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Product Code. 16898944 Shop All Proteintech Products
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16898944 20 μL 20µL
16888944 150 μL 150µL
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Product Code. 16898944 Supplier Proteintech Supplier No. 192791AP20UL
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Rabbit Polyclonal Antibody

This antibody is specific to isoform p71 and isoform p69 of OAS2.

This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2′-specific nucleotidyl transfer reactions to synthesize 2′,5′-oligoadenylates. These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.

Specifications

Antigen OAS2
Applications Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.33 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene OAS2
Gene Accession No. E9Q9A9, P29728
Gene Alias (2 5)oligo(A) synthase 2, 2 5 oligoadenylate synthase 2, 2 5A synthase 2, OAS2, p69 OAS / p71 OAS, p69OAS / p71OAS
Gene Symbols OAS2
Host Species Rabbit
Immunogen OAS2 Fusion Protein Ag6170
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 246728, 4939
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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