missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Cell Culture Media, Supplements, and Reagents
  4. Cell Culture Reagents, Antibiotics and Supplements
  5. Antibiotics
  6. 17620907

Nystatin, MP Biomedicals™

Product Code. 17620907 Shop All MP Biomedicals Products
Change view
Click to view available options
Quantity:
500 kU
Förpackningsstorlek:
500ku
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Produktkod. Quantity unitSize
17620907 500 kU 500ku
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Denna artikel kan inte returneras. Se returpolicy
Produktkod. 17620907 Leverantör MP Biomedicals Leverantörsnummer 02194534.5

Please to purchase this item. Need a web account? Register with us today!

Denna artikel kan inte returneras. Se returpolicy

Beskrivning

Nystatin is an antifungal antibiotic obtained from Streptomyces noursei.

Nystatin A is closely related to Amphotericin B. Each is a macrocyclic lactone containing a ketal ring, an all-trans polyene system, and a mycosamine (3-amino-3-deoxyrhamnose) moiety. Nystatin probably acts by binding to sterols in the cell membrane of the fungus with a resultant change in membrane permeability allowing leakage of intracellular components. It is absorbed very sparingly following oral administration. Most of the orally administered nystatin is passed unchanged in the stool.

  • Nystatin acts by binding to ergosterols in fungal cell membranes, increasing permeability of the membrane, and creating nystatin/ergosterol based ion channels.
  • It also functions as a lipid raft-inhibiting reagent and as membrane associated cholesterol.
  • It is known to be a mixture, but the composition has not been completely elucidated.
  • Working concentration is 50mg/L for yeasts and fungi.
    TRUSTED_SUSTAINABILITY

    Specifikationer

    Physical Form Powder
    Absorbance 290, 305, 320 ± 2nm (max (ethanol))
    CAS 1400-61-9
    pH 6 to 8 (3% aq. soln.)
    Melting Point >160°C (literature)
    Loss on Drying <8%
    Quantity 500 kU
    Molecular Formula C47H75NO17
    Validated Application Cell Culture
    Synonym Mycostatin; Fungicidin
    Solubility Information Very slightly soluble in water (effective as a suspension); slightly to sparingly soluble in alcohol, in methanol, in n-propyl alcohol, and in n-butyl alcohol; insoluble in chloroform, in ether, and in benzene.
    InChI Key VQOXZBDYSJBXMA-AWCIUYGFSA-N
    SMILES CC1C=CC=CCCC=CC=CC=CC=CC(CC2C(C(CC(O2)(CC(C(CCC(CC(CC(CC(=O)OC(C(C1O)C)C)O)O)O)O)O)O)O)C(=O)O)OC3C(C(C(C(O3)C)O)N)O
    IUPAC Name (1S,3R,6Z,18S,19R,20S,21S,25S,27S,29S,32R,33S,35S,37S,38R)-3-[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-19,25,27,29,32,33,35,37-octahydroxy-18,20,21-trimethyl-23-oxo-22,39-dioxabicyclo[33.3.1]nonatriaconta-4,6,8,10,14,16-hexaene-38-carb
    Molecular Weight (g/mol) 926.107
    PubChem CID 133640190
    Formula Weight 926.11g/mol
    Grade Cell Culture
    Visa mer Visa mindre
    Produkttitel
    Välj ett problem

    Genom att klicka på Skicka bekräftar du att du kan bli kontaktad av Fisher Scientific angående feedbacken du har lämnat i detta formulär. Vi kommer inte att dela din information för andra ändamål. All kontaktinformation som tillhandahålls ska också underhållas i enlighet med vår Sekretesspolicy.