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Numidargistat dihydrochloride, MedChemExpress

Product Code. 16483668
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Product Code. 16483668 Supplier Medchem Express Supplier No. HY101979A

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Description

MedChemExpress Numidargistat (CB-1158) dihydrochloride is a potent and orally active inhibitor of arginase, with IC50s of 86 nM and 296 nM for recombinant human arginase 1 and recombinant human arginase 2, respectively. Immuno-oncology agent.

Numidargistat (CB-1158) dihydrochloride is a potent and orally active inhibitor of arginase, with IC50s of 86 nM and 296 nM for recombinant human arginase 1 and recombinant human arginase 2, respectively. Immuno-oncology agent.

Specifications

Chemical Name or Material Numidargistat dihydrochloride
Color White
Purity Grade Notes Research
Molecular Formula C11H24BCl2N3O5
Quantity 10 mg
Synonym CB-1158 dihydrochlorideINCB01158 dihydrochloride
Solubility Information DMSO : 55 mg/mL (152.76 mM; Need ultrasonic) ∣H2O : 37.78 mg/mL (104.93 mM; Need ultrasonic)
SMILES O=C([C@@H](N)C)N1C[C@H](CCCB(O)O)[C@](N)(C(O)=O)C1.Cl.Cl
Molecular Weight (g/mol) 360.04
Formula Weight 360.04
Percent Purity 95.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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