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Tocris Bioscience™ NS 9283
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Product Code. 18756248
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Product Code. 18756248 Supplier Tocris Bioscience™ Supplier No. 5112/10

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Positive allosteric modulator of α4β2 nAChRs

NS 9283 is a positive allosteric modulator of α4β2 receptor; increases the potency of Ach-evoked currents ∼60 fold without affecting the maximum efficacy (HEK293-hα4β2 cells). Reduces the rate of recovery from desensitization and slows the rate of deactivation. Displays a synergistic effect on the Emax when given with NS206 at 3α:2β receptors.
TRUSTED_SUSTAINABILITY

Specifications

Quantity 10 mg
Product Type NS 9283
Purity >99%
Molecular Weight (g/mol) 248.24
Inhibitors NS 9283

For Research Use Only

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