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  5. Tocris Bioscience™ NS 19504

Tocris Bioscience™ NS 19504

Product Code. 18710488
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50 mg
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18710488 10 mg 10mg
18763429 50 mg 50mg
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Product Code. 18710488 Supplier Tocris Bioscience™ Supplier No. 5276/10

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147.90 EUR valid until 2026-03-31
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Description

KCa1.1 (BK) channel activator

NS 19504 is a selective activator of large-conductance Ca2+-activated potassium channels (BKCa, KCa1.1) (EC50 = 11 μM). Activates BK channels in native smooth muscle cells from guinea pig bladder and reduces spontaneous phasic contractions in bladder strips ex vivo. Displays no effect on contractions induced by a high K+ concentration or at 65 other receptors tested, including L- and N- type Ca2+ channels, Nav, KATP and hERG channels.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material 5-[(4-Bromophenyl)methyl]-2-thiazolamine
CAS 327062-46-4
Quantity 10 mg
Target Ca2+-Activated Potassium Channel Activators
Molecular Formula C10H9BrN2S
Formula Weight 269.16
Purity >99%
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