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Tocris Bioscience™ NS 19504
KCa1.1 (BK) channel activator
Brand: Tocris Bioscience™ 5276/50
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Description
NS 19504 is a selective activator of large-conductance Ca2+-activated potassium channels (BKCa, KCa1.1) (EC50 = 11 μM). Activates BK channels in native smooth muscle cells from guinea pig bladder and reduces spontaneous phasic contractions in bladder strips ex vivo. Displays no effect on contractions induced by a high K+ concentration or at 65 other receptors tested, including L- and N- type Ca2+ channels, Nav, KATP and hERG channels.Specifications
| 5-[(4-Bromophenyl)methyl]-2-thiazolamine | |
| 327062-46-4 | |
| 50 mg |
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