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Invitrogen™ NRL Polyclonal Antibody
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Product Code. 16608184
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. Quantity unitSize
16608184 100 μL 100µL
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Product Code. 16608184 Supplier Invitrogen™ Supplier No. PA5101705

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total NRL.

Nrl (neural retina leucine zipper) is a member of the Maf family of transcription factors, which characteristically contain a highly conserved basic leucine zipper (bZIP)-DNA binding motif. Both Nrl and c-Maf preferentially bind to T-MARE sites and are implicated in a wide variety of developmental and physiologic roles. The Maf-Nrl subfamily regulates the expression of cell type-specific genes in tissues of the hematopoietic system, cerebellum and developing hindbrain. Maf and Nrl proteins bind an extended AP-1-like sequence and can form heterodimers with Fos and Jun transcription factors. In retinal cells and photoreceptor cells, Nrl promotes the expression of rhodopsin through binding to the Nrl response element present in the rhodopsin promoter. Nrl is expressed throughout the developing central and peripheral nervous system during neuronal differentiation, and its expression is restricted to neocortex, brainstem and retinal neurons during adulthood.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NRL
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene NRL
Gene Accession No. P54845, P54846
Gene Alias D14H14S46E; D14S46E; neural retina leucine zipper; neural retina leucine zipper gene; neural retinal-specific leucine zipper; neural retina-specific leucine zipper protein; Nrl; NRL-MAF; RP27
Gene Symbols NRL
Host Species Rabbit
Immunogen A synthesized peptide derived from human NRL(Accession P54845), corresponding to amino acid residues M1-P49.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18185, 4901
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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