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Invitrogen™ NPY Monoclonal Antibody (8)
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Product Code. 11584132
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400 μL
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11584132 400 μL Each
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Product Code. 11584132 Supplier Invitrogen™ Supplier No. ABS0280802

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Description

Mouse Monoclonal Antibody

ABS 028-08-02 detects Neuropeptide Y in human and rat samples. ABS 028-08-02 has been successfully used in ELISA and immunohistochemistry (paraffin) procedures. NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL.

This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase, regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NPY
Applications ELISA, Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Monoclonal
Clone 8
Concentration 1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with 15mM sodium azide; pH 7.4
Gene NPY
Gene Accession No. P01303, P07808, P57774
Gene Alias 0710005A05Rik; C-flanking peptide of NPY; CPON; involved in appetite regulation; LOC100912228; Neuropeptide tyrosine; Neuropeptide Y; neuropeptide Y precursor; Neuropeptide-Y; Npy; NPY02; OTTHUMP00000201947; prepro-neuropeptide Y; proneuropeptide Y; pro-neuropeptide Y; pro-neuropeptide Y-like; PYY4; RATNPY; RATNPY02
Gene Symbols NPY
Host Species Mouse
Immunogen Synthetic peptide made to human/rat NPY.
Purification Method Protein A
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100912228, 109648, 24604, 4852
Target Species Human, Mouse, Rat
Content And Storage 4°C, store in dark
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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