missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Benzenoids
  6. Benzene and substituted derivatives
  7. Phenoxy compounds
  8. NPS-2143, MedChemExpress

NPS-2143, MedChemExpress

Product Code. 16462768
Encompass_Preferred
Change view
Click to view available options
Quantity:
5 mg
10 mg
50 mg
100 mg
Unit Size:
100mg
10mg
50mg
5mg
4 product options available for selection
Product selection table with 4 available options. Use arrow keys to navigate and Enter or Space to select.
Product Code. Quantity unitSize
16462768 10 mg 10mg
16455507 5 mg 5mg
16439466 50 mg 50mg
16444226 100 mg 100mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 4 options available.
4 options
This item is not returnable. View return policy
Product Code. 16462768 Supplier Medchem Express Supplier No. HY10007

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

MedChemExpress NPS-2143 (SB-262470A), an orally active calcilytic agent, is a selective and potent calcium ion-sensing receptor (CaSR) antagonist. NPS-2143 (SB-262470A) blocks increases in cytoplasmic Ca2+ concentrations (IC50=43 nM) elicited by activating the Ca2+ receptor in HEK 293 cells expressing the human Ca2+ receptor.

NPS-2143 (SB-262470A), an orally active calcilytic agent, is a selective and potent calcium ion-sensing receptor (CaSR) antagonist. NPS-2143 (SB-262470A) blocks increases in cytoplasmic Ca2+ concentrations (IC50=43 nM) elicited by activating the Ca2+ receptor in HEK 293 cells expressing the human Ca2+ receptor.

Specifications

Chemical Name or Material NPS-2143
CAS 284035-33-2
Color Off-White
Purity Grade Notes Research
Molecular Formula C24H25ClN2O2
Quantity 10 mg
Synonym SB-262470A
Solubility Information DMSO : 17.86 mg/mL (43.68 mM; ultrasonic and adjust pH to 2 with H2O)
SMILES N#CC1=C(OC[C@@H](CNC(C)(CC2=CC=C3C=CC=CC3=C2)C)O)C=CC=C1Cl
Molecular Weight (g/mol) 408.92
Formula Weight 408.92
Percent Purity 98.09%
Grade Research
Physical Form Solid
For Use With (Application) Metabolism-protein/nucleotide metabolism
Show More Show Less

Research purposes only

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.