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NF1 Monoclonal Antibody (McNFn27b), Invitrogen™

Product Code. 11518852
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Quantity:
200 μg
Unit Size:
200µg
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11518852 200 μg 200µg
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Product Code. 11518852 Supplier Invitrogen Supplier No. MA1085

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Description

Mouse Monoclonal Antibody

MA1-085 detects neurofibromin in human, rat, and mouse cells. MA1-085 has been successfully used in Western blot, and immunohistochemistry procedures. By Western blot, this antibody detects a ∽240-260 kDa protein. The MA1-085 immunogen is a synthetic peptide corresponding to the N-terminal residues 27-41 of human neurofibromin.

The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NF1
Applications Immunocytochemistry, Immunohistochemistry, Western Blot
Classification Monoclonal
Clone McNFn27b
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1mg/mL BSA and 0.05% sodium azide
Gene NF1
Gene Accession No. P21359, P97526, Q04690
Gene Alias AW494271; DKFZp686J1293; E030030H24Rik; FLJ21220; neurofibromatosis 1; Neurofibromatosis type 1; neurofibromatosis-related protein NF-1; Neurofibromin; neurofibromin 1; Neurofibromin truncated; NF1; Nf-1; NFNS; VRNF; WSS
Gene Symbols NF1
Host Species Mouse
Immunogen Synthetic peptide corresponding to the N-terminal residues 27-41 of human neurofibromin.
Purification Method Protein G
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18015, 24592, 4763
Target Species Human, Mouse, Rat
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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