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Invitrogen™ Nectin 2 Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA592433
Description
Immunogen sequence: FILLRVRRRR KSPGGAGGGA SGDGGFYDPK AQVLGNGDPV FWTPVVPGPM EPDGKDEEEE EEEEKAEKGL MLPPPPALED DMESQLDGSL ISRRAVYV; Positive Samples: MCF-7, SW620, A-549, SKOV3; Cellular Location: Cell membrane, Single-pass type I membrane protein.
This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Specifications
| Nectin 2 | |
| Polyclonal | |
| Unconjugated | |
| NECTIN2 | |
| AI325026; AI987993; CD112; herpes virus entry mediator B; Herpesvirus entry mediator B; herpesvirus entry protein B; hveB; mHveB; MPH; Murine herpes virus entry protein B; murine herpesvirus entry protein B; nectin cell adhesion molecule 2; Nectin2; Nectin-2; Poliovirus receptor homolog; poliovirus receptor related 2; poliovirus receptor-like 2; poliovirus receptor-related 2; poliovirus receptor-related 2 (herpesvirus entry mediator B); poliovirus receptor-related protein 2; poliovirus sensitivity; PRR2; Pvr; Pvrl2; PVRR2; Pvs | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 5819 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| ELISA, Western Blot | |
| 1.41 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| Q92692 | |
| NECTIN2 | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 382-479 of human Nectin 2/CD112 (NP_0028471). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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