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Invitrogen™ MYOD Monoclonal Antibody (5.8A)
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Product Code. 11394733
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Quantity:
500 μL
Unit Size:
500µL
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11394733 500 μL 500µL
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Product Code. 11394733 Supplier Invitrogen™ Supplier No. MA512902

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Description

Mouse Monoclonal Antibody

MA5-12902 targets MyoD1 in IF, IM, and IP applications and shows reactivity with Chicken, Human, mouse, and Rat samples. The MA5-12902 immunogen is recombinant mouse MyoD1 protein.

The Myogenic determination gene (MyoD) was first identified by the virtue of its ability to convert embryonic mouse fibroblast cells to muscle cells. It was subsequently shown that forced expression of MyoD (human homolog is myf 3) gene in a wide variety of normal and neoplastic cells could either convert the cells to muscle cells or activate a set of the otherwise transcriptionally inactive muscle-specific genes in these cells. The regulatory domain of the MyoD gene product lies within a 70 amino acid region and comprises a basic DNA binding motif and a helix-loop-helix (HLH) dimerization motif. Subsequent studies identified three other genes whose products shared sequence homology for the basic HLH domain of MyoD. These are; myf5, myogenin (human homolog is myf4) and myf6 (also known as MRF4 and herculin).
TRUSTED_SUSTAINABILITY

Specifications

Antigen MYOD
Applications Immunomicroscopy, Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 5.8A
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA and 0.05% sodium azide; pH 7.4
Gene MYOD1
Gene Accession No. P10085, P15172, P16075, Q02346
Gene Alias AI503393; bHLHc1; Class C basic helix-loop-helix protein 1; CMD1; MYF3; Myf-3; Myoblast determination protein 1; myoblast determination protein 1 homolog; Myod; MYOD1; Myod-1; MYOD1 homolog; myogenic differentiation 1; myogenic factor 1; myogenic factor 3; PUM; unnamed protein product
Gene Symbols MYOD1
Host Species Mouse
Immunogen Recombinant mouse MyoD1 protein.
Purification Method Protein A/G
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17927, 337868, 374048, 4654
Target Species Chicken, Human, Mouse, Rat
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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