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Invitrogen™ MRPL11 Polyclonal Antibody
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Product Code. 16519151
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Quantity:
100 μL
Unit Size:
100µL
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16519151 100 μL 100µL
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Product Code. 16519151 Supplier Invitrogen™ Supplier No. PA596308

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MSKLGRAARG LRKPEVGGVI RAIVRAGLAM PGPPLGPVLG QRGVSINQFC KEFNERTKDI KEGIPLPTKI LVKPDRTFEI KIGQPTVSYF LKAAAGIEKG ARQTGKEVAG LVTLKHVYEI ARIKAQDEAF ALQDVPLSSV VRSIIGSARS LGIRVVKDLS SEELAAFQKE RAIFLAAQKE ADLAAQEEAA KK; Positive Samples: HepG2, HeLa, MCF7, A-549, Mouse kidney, Mouse brain, Mouse heart, Rat heart; Cellular Location: Mitochondrion.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants that encode different isoforms. Pseudogenes corresponding to this gene are found on chromosomes 5q and 12q.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MRPL11
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene MRPL11
Gene Accession No. Q5XIE3, Q9CQF0, Q9Y3B7
Gene Alias 2410001P07Rik; 39S ribosomal protein L11, mitochondrial; CGI-113; cgi-113 protein; L11mt; mgc111024; Mitochondrial large ribosomal subunit protein uL11m; mitochondrial ribosomal protein L11; Mrpl11; MRP-L11
Gene Symbols MRPL11
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-192 of human MRPL11 (NP_0571341).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 293666, 65003, 66419
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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