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E2F3, Mouse, Polyclonal Antibody, Abnova™
Mouse polyclonal antibody raised against a full-length recombinant E2F3.
Brand: Abnova H00001871-A01.50uL
Description
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F2, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner. [provided by RefSeq
Sequence: MQSGGGVKTDDTSTLNSLCGYAWVYVWEEKQRCRLSSFFSSSASIPGLLPSHTLDLVQNVGVVLDEALGWGRERELCVKCLLEMHCGVFSCMGNHLCQAFPHFPYLSHLVSCLCFQLCVILFASCTKLIFSKVSpecifications
| E2F3 | |
| Polyclonal | |
| Mouse polyclonal antibody raised against a full-length recombinant E2F3. | |
| E2F3 | |
| DKFZp686C18211/E2F-3/KIAA0075/MGC104598 | |
| Mouse | |
| 50 μL | |
| Primary | |
| Human | |
| Antisera |
| ELISA, Western Blot | |
| Unconjugated | |
| 50% glycerol | |
| BC016847 | |
| E2F3 | |
| E2F3 (AAH16847, 1 a.a. to 133 a.a) full-length recombinant protein with GST tag. | |
| RUO | |
| 1871 | |
| Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
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