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Tocris Bioscience™ MMG 11

Product Code. 18749106
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18736686 10 mg 10mg
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Product Code. 18749106 Supplier Tocris Bioscience™ Supplier No. 6858/50

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TLR2 antagonist

MMG 11 is a TLR2 antagonist (IC50 values are in the range 1.7 - 5.7 μM). Exhibits selectivity for TLR2 over TLR4, TLR5, TLR7/8 and TLR9. Reduces TLR2-mediated cytokine secretion from PBMCs. MMG 11 preferentially inhibits TLR2/1- over TLR2/6-mediated NK-κB activation (IC50 values are 0.87 and 7.4 μM, respectively).
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Specifications

Chemical Name or Material Ethyl 5-(2-oxo-2-(2,3,4-trihydroxyphenyl)ethyl)furan-2-carboxylate
CAS 313254-94-3
Quantity 50 mg
Target Toll-like Receptor Antagonists
Molecular Formula C15H14O7
Formula Weight 5252
Purity 97%
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