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Tocris Bioscience™ MMG 11
Description
MMG 11 is a TLR2 antagonist (IC50 values are in the range 1.7 - 5.7 μM). Exhibits selectivity for TLR2 over TLR4, TLR5, TLR7/8 and TLR9. Reduces TLR2-mediated cytokine secretion from PBMCs. MMG 11 preferentially inhibits TLR2/1- over TLR2/6-mediated NK-κB activation (IC50 values are 0.87 and 7.4 μM, respectively).
Specifications
Specifications
| Chemical Name or Material | Ethyl 5-(2-oxo-2-(2,3,4-trihydroxyphenyl)ethyl)furan-2-carboxylate |
| CAS | 313254-94-3 |
| Quantity | 10 mg |
| Target | Toll-like Receptor Antagonists |
| Molecular Formula | C15H14O7 |
| Formula Weight | 1414 |
| Purity | 97% |
Product Title
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