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Invitrogen™ MLPH Polyclonal Antibody
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Product Code. 17471723 Shop All Thermo Scientific Products
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100 μL
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100µL
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17471723 100 μL 100µL
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Product Code. 17471723 Supplier Invitrogen™ Supplier No. PA5118065

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Rabbit Polyclonal Antibody

MLPH Polyclonal Antibody for Western Blot, IHC (P), IP

Slac2-a (for synaptotagmin-like protein (Slp) homolog lacking C2 domains-a) links Rab27A on melanosomes with Myosin VA in melanocytes. Slac2-a binds Myosin VA through a C-terminal region and GTP-bound Rab27A through its synaptotagmin-like protein homology domain (SHD), which is located near the N-terminus. The transport of pigment and cytotoxic granules in melanocytes requires the stable formation of this complex, and thus mutations in the binding domains of the three protein components may cause albinism and/or severe immune disorders.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MLPH
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation PBS with 0.03% ProClin 300; pH 7
Gene Mlph
Gene Accession No. Q9BV36
Gene Alias 2210418F23Rik; 5031433I09Rik; AW228792; D1Wsu84e; Exophilin-3; l(1)-3Rk; l1Rk3; leaden; leaden protein; Ln; Melanophilin; MGC2771; MGC59733; Mlph; OTTMUSP00000025451; SLAC2A; Slac-2a; SlaC2-a; Slp homolog lacking C2 domains a; synaptotagmin-like protein 2a
Gene Symbols Mlph
Host Species Rabbit
Immunogen E. coli-derived Human MLPH/Melanophilin fragment.
Purification Method Antigen affinity chromatography, Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 79083
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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