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  7. MK-2206 dihydrochloride, MedChemExpress

MK-2206 dihydrochloride, MedChemExpress

Product Code. 16496587
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Product Code. 16496587

Brand: Medchem Express HY10358

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Description

MedChemExpress MK-2206 dihydrochloride (MK-2206 (2HCl)) is an orally active allosteric AKT inhibitor with IC50s of 5 nM, 12 nM, and 65 nM for AKT1, AKT2, and AKT3, respectively. MK-2206 dihydrochloride induces autophagy.

MK-2206 dihydrochloride (MK-2206 (2HCl)) is an orally active allosteric AKT inhibitor with IC50s of 5 nM, 12 nM, and 65 nM for AKT1, AKT2, and AKT3, respectively. MK-2206 dihydrochloride induces autophagy.

Specifications

Chemical Name or Material MK-2206 dihydrochloride
CAS 1032350-13-2
Color Green Yellow
Purity Grade Notes Research
Molecular Formula C25H23Cl2N5O
Quantity 5 mg
Synonym MK-2206 (2HCl)
Solubility Information DMSO : 16.67 mg/mL (34.70 mM; ultrasonic and warming and heat to 70°C) ∣H2O : 3.57 mg/mL (7.43 mM; ultrasonic and warming and heat to 60°C)
SMILES O=C1N2C(C3=CC(C4=CC=CC=C4)=C(N=C3C=C2)C5=CC=C(C6(N)CCC6)C=C5)=NN1.Cl.Cl
Molecular Weight (g/mol) 480.39
Formula Weight 480.39
Percent Purity 98.89%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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