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Description
Immunogen sequence: QQHQALQTNW HLPQMSSPPS AARHSLCLQP DSGGPPELGS SPPVLCSNSS SLGSSTPTGA ACAPGDYGRQ ALSPAEAEKR SGGKR Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 96%.
Mesodermal transcription factor that plays a key role in somitogenesis and is required for sclerotome development. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle.
Specifications
Specifications
| Antigen | MEOX2 |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 0.2 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | MEOX2 |
| Gene Accession No. | P50222 |
| Gene Alias | AI528662; GAX; Growth arrest-specific homeobox; homeobox protein MOX-2; MEOX2; mesenchyme homeo box 2 (growth arrest-specific homeo box); mesenchyme homeobox 2; Mox2; Mox-2 |
| Gene Symbols | MEOX2 |
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Product Title
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