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Invitrogen™ LRRK2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA585363
This item is not returnable.
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Description
Keep as concentrated solution. Predicted reactivity: Mouse (82%), Rat (80%), Pig (92%), Bovine (87%). Positive Control: NT2D1, IMR32, U87-MG, MCF-7, mouse cerebellum. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain. Mutations in LRRK2 have been associated with Parkinson's disease. LRRK2 is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane.
Specifications
| LRRK2 | |
| Polyclonal | |
| Unconjugated | |
| LRRK2 | |
| 4921513O20Rik; 9330188B09Rik; augmented in rheumatoid arthritis 17; AURA17; AW561911; BC 300-268; cI-46; D630001M17Rik; DARDARIN; DKFZp434H2111; FLJ45829; Gm927; leucine rich repeat kinase 2; leucine-rich repeat kinase 2; leucine-rich repeat serine/threonine-protein kinase 2; LRR kinase 2; LRRK 2; Lrrk2; LRRK-2; PARK8; RIPK7; ROCO2 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 120892, 66725 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot | |
| 1 mg/mL | |
| 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7 | |
| Q5S006, Q5S007 | |
| LRRK2 | |
| Recombinant protein encompassing a sequence within the center region of human LRRK2. | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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