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Lomibuvir, MedChemExpress
MedChemExpress Lomibuvir (VX-222), a selective, non-nucleoside polymerase inhibitor, targets thumb pocket 2 of the HCV NS5B polymerase (RdRp) with a Kd of 17 nM. Lomibuvir inhibits the 1b/Con1 HCV subgenomic replicon with an EC50 of 5.2 nM. Lomibuvir preferentially inhibits elongative RNA synthesis rather than de novo-initiated RNA synthesis.
167.40 € - 878.85 €
Specifications
| Chemical Name or Material | Lomibuvir |
|---|---|
| CAS | 1026785-55-6 |
| Color | White |
| Purity Grade Notes | Research |
| Molecular Formula | C25H35NO4S |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
16488198
|
Medchem Express
HY-75800 |
10 mg |
292.95 €
10mg |
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|
16480638
|
Medchem Express
HY-75800 |
5 mg |
167.40 €
5mg |
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|
16464097
|
Medchem Express
HY-75800 |
50 mg |
878.85 €
50mg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
Lomibuvir (VX-222), a selective, non-nucleoside polymerase inhibitor, targets thumb pocket 2 of the HCV NS5B polymerase (RdRp) with a Kd of 17 nM. Lomibuvir inhibits the 1b/Con1 HCV subgenomic replicon with an EC50 of 5.2 nM. Lomibuvir preferentially inhibits elongative RNA synthesis rather than de novo-initiated RNA synthesis.Specifications
| Lomibuvir | |
| White | |
| C25H35NO4S | |
| DMSO : 100 mg/mL (224.41 mM; Need ultrasonic) | |
| 445.61 | |
| 98.97% | |
| Solid |
| 1026785-55-6 | |
| Research | |
| VX-222 | |
| O=C(C1=C(N([C@@H]2CC[C@@H](O)CC2)C([C@H]3CC[C@H](C)CC3)=O)C=C(C#CC(C)(C)C)S1)O | |
| 445.61 | |
| Research | |
| COVID-19-anti-virus |
Safety and Handling
missing translation for 'shelfLife' : Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Recommended Storage : Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Research purposes only
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