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Lenalidomide, MedChemExpress

Product Code. 16441966
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Artikelnummer. 16441966 Leverandør Medchem Express Leverandørnr. HYA0003

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Beskrivelse

MedChemExpress Lenalidomide (CC-5013), a derivative of Thalidomide, acts as molecular glue.

Lenalidomide is an orally active immunomodulator. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide (CC-5013) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells.

Tekniske data

Chemical Name or Material Lenalidomide
CAS 191732-72-6
Color Off-White
Purity Grade Notes Research
Molecular Formula C13H13N3O3
Quantity 500 mg
Synonym CC-5013
Solubility Information DMSO : 100 mg/mL (385.71 mM; Need ultrasonic)
SMILES O=C1C2=CC=CC(N)=C2CN1C(C(N3)=O)CCC3=O
Molecular Weight (g/mol) 259.26
Formula Weight 259.26
Percent Purity 99.05%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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